[How to eat fish fillets]_How to make_How to make

銆愰奔鐗囨€庝箞鍋氬ソ鍚冦€慱鍒朵綔鏂规硶_濡備綍鍒朵綔
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[Does chicken leg soup stew nutritious?】 _Chicken legs, stew_How to make

銆 愰 Floating canisters fortifications 撣 栨 湁 撀 ュ 吇 咫 娉 囉 囪 犆 楱 否 吣, 鉣 栨 堡 _ 賣 庝 箞 锅?
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[How to adjust the white noodle pancake batter]_Home cooking_Method

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Debon (603056): Profit growth declines and waits for turning point in performance

Debon (603056): Profit growth declines and waits for turning point in performance

The main points of the report describe the first three quarters of 2019, Debon realized revenue of 184.

5 ppm, an increase of 14 in ten years.

9%, realized net profit attributable1.

100 million, down 75 a year.

7%, corresponding to EPS is 0.

12 yuan; of which, the company achieved revenue of 65 in the third quarter.

6 ppm, an increase of 11 in ten years.

9%, achieving net profit attributable to 604.

60,000 yuan, down 96 every year.

0%, realizing deduction of non-attributable net profit -0.

9 trillion, a year of 182.

9%.

The event commented on the growth rate of large-scale express delivery, and the express flow diversion effect subsided.

In the third quarter of 2019, the company’s revenue increased by 10 in ten years.

9%, the growth rate decreased by 4 from the previous month.

9pct, the main reason for the growth or revenue of large express delivery business.

From the perspective of product structure, in terms of large-scale express delivery, the unit price of large-scale express delivery is expected to decline by the continuation of the strategy of sterilization of revenue in the first half of the year and the intensified competition in the industry, resulting in an increase of 21 in the third quarter.

0%, a growth rate of 28 in the first half of the year.

8 points; In terms of express shipping, due to the macroeconomic impact, the overall industry demand is sluggish, and the company’s fast operating receipts have only increased by 1.

2%, but the shunting effect of large-scale express delivery on express delivery has basically subsided, and the growth rate of fast-operating revenue in the third quarter has changed from negative to positive.

Capacity expansion dragged down performance, and management performance continued to improve.

The company’s gross profit margin in the third quarter was only 7.

7%, the second lowest point since 2017, the same month-on-month significant replacement (-5.

9pct, -4.

3pct), mainly due to the company ‘s continued increase in manpower and transportation expenses in the third quarter, cost growth rate was greater than revenue growth rate, and production capacity exceeded expectations.

Regarding the expense ratio, due to the previous informatization construction expenditure, management performance has gradually improved, and the expense ratio decreased during the third quarter.

0 points to 9.

1%.

In the end, dragged down by the sharp increase in gross profit margin, the company’s net interest rate fell.

5pct to 0.

1%.

Investment suggestion: Pessimistic expectations are sufficient, waiting for the turning point in performance.

Considering: 1) The company is a leader in the domestic less-than-truckload sector, and the transformation of large-scale express delivery services has become a first-mover advantage, and the future business scale and gross profit margin are expected to continue to increase; 3) Mr. Cui Weixing, the founder, returns to the front line of management, rebuilding execution and responding to confidenceThe recovery may promote the company ‘s performance to gradually recover. 3) The current PE valuation of the company is at its lowest point since listing, and pessimistic expectations are relatively sufficient. At the same time, considering the company ‘s rare national direct express network, the network replacement cost may be higher than the current one.Market value must be a margin of safety.

Taking into account that the current degree of competition in the large-scale express market is higher than expected, we adjust the company’s profit forecast, but maintain the “Buy” rating and expect the company’s EPS to 0 in 2019-2021.

33, 0.

55 and 0.

62 yuan, corresponding to the current sustainable PE estimates are 38,北京夜网 22 and 20 times respectively.

Risk Warning: 1. Market demand has grown significantly; 2.

Increasing competition in the industry has dragged down the company’s profits; 3.

The low cost of capital expenditures has increased significantly.

SAIC Group (600104) 2019 Interim Report Review: Temporarily Shortens the Turning Point

SAIC Group (600104) 2019 Interim Report Review: Temporarily Shortens the Turning Point

Profits are twice a year27.

49%, performance in line with expectations The company achieved revenue of 3762 in the first half.

93 trillion, down 19 a year.

05%, net profit attributable to mother 137.

6.4 billion, down 27 each year.

49%, net profit after deduction is 124.

95 ‰, a decrease of 27 per year.

61%.

Realized revenue of 1802 in the second quarter.

78 ppm, a decrease of 21 per year.

62%, net profit attributable to mother 55.

1.3 billion, down 40 a year.

56%, net profit after deduction is 48.

91 trillion, down 42 a year.

01%.

The margin of the company is larger than the revenue, which is mainly caused by the increase in the production capacity of the automakers and the increase in terminal discounts. Overall, the first half of the performance was in line with our expectations.

Companies with differences in the average value of each profit segment came from Volkswagen, GM, Huayu Investment Income, SAIC Finance and GM Wuling’s profit proportions were 39.

9%, 21.

7%, 5.

8%, 12.

9%, 12.

9% (2018 data).

Affected by the sharp expansion of the automotive industry in the first half of the year, the overall sales of 19H1 declined 9.

94%, GM sales temporarily decreased by 12.

91%, SAIC passenger car sales increased by 13.
%.

18%, SAIC-GM-Wuling sales increased by 29.

19%, the company’s overall sales in 19H1 increased by 16.

62%.

Volkswagen revenue fell 19 year-on-year.

15%, profit fell 36% year-on-year.

14%.

GM revenue fell by 18 in ten years.

34%, with profits falling by 30 per year.

59%.

Wuling’s revenue fell 28 in ten years.

91%, profit dropped 58.

68%.
SAIC’s investment revenue increased by 9 in ten years.
53%, with profits increasing by 2 per year.

33%.

The 苏州夜网论坛 investment income from Huayu is every 29 years.

53%.

The average change in the business impact of the company’s various business segments is mainly due to the volume change and the increase in terminal discounts at the same time. The change in the final profit end exceeds the decrease in the sales range.

Risks suggest that the auto market will pick up less than expected in the second half of the year, and competition will continue to increase.

Investment logic: significant short-term and short-term, waiting for the turning point of the industry to take into account changes in the industry and the company’s sales volume in the first half of the year. At the same time, the company’s mid-year shift has reduced its sales target to 6.5 million units, a reduction of 600,000 units from its initial target of 7.1 million 杭州桑拿 units.The reduction in sales volume growth elasticity is -8.

5%, the adjusted target is reduced by 7 for the last time each year.

8%.

Therefore, we have revised down the company’s profit forecast for 19-20, and we estimate that the net profit attributable to mothers in 19/20/21 will be 304 respectively.

21/342.

60/374.

9.1 billion (early military forecasts for 19/20 net profit attributable to mothers are 403.

54/434.

2.7 billion), and the reasonable estimate range after the reduction is 29.

30-35.

16 yuan (corresponding to 10-12x PE in 2020), the reasonable variable interval for budget forecast is 37.

20-44.

64 yuan, considering that the auto market is expected to recover in the second half of the year and the company’s leading advantages, it is expected to usher in volume and profit improvement, and maintain a “buy” rating.

Sun Paper (002078) Quarterly Report Review 2019: Profitability Improves QoQ New Project Smoothly Advances 2019 Profit Expected Quarterly

Sun Paper (002078) Quarterly Report Review 2019: Profitability Improves QoQ New Project Smoothly Advances 2019 Profit Expected Quarterly

The company announced the first quarter report of 2019, realizing net profit attributable to mothers3.

80 trillion, slightly more than we expected.

The company announced the first quarter report of 2019, and realized revenue 54 from January to March 2019.

51 ppm, a ten-year increase of 8.

1%; operating profit 4.

30,000 yuan, an average of 54 in ten years.

9%, an increase of 32 from the previous month.

0%; corresponding to the net profit of the mother 3.

80 ‰, 38 years ago.

3%; deduct non-attributed net profit 3.

34 billion, 44 from the previous decade.

7%, the main subsidy for non-recurring gains and losses.

Laos dissolves phenols and contributes to the increase in performance.

The production of Laos dissolving pulp project has entered a stable period, and the cost advantage is prominent, contributing to the first quarter of 2019 performance increase.

With the initial increase in prices for double-coated paper and coated paper from February, high-priced pulp stocks have been gradually digested, and the company’s pulp and paper profitability has been optimized monthly.

The company’s comprehensive gross profit margin for Q1 2019 was 17.

7%, an increase of 0 from the previous month.

36 points.

After the holiday, paper prices have experienced multiple rounds of rise, and the profitability of the Q2 pulp and paper system will be further repaired.

After the Spring Festival, distributors and downstream printing plants replenished the goods, and in March each year, the publishing house invited tenders for autumn textbooks. Cultural paper ushered in the small spring season.

In January 2019, paper mills issued price increases in February, and double offset paper and coated paper were raised by 200 yuan / ton respectively; at the end of February 2019, at the end of March and at the end of April, a new round of price increase letters were issued: double offsetCoated paper continued to rise by 200 yuan / ton.

According to the data of Paper Union, the company’s double offset paper and coated paper (Golden Sun, Huaxia Sun) will be converted to raise the price of the terminal 300 years later?
400 yuan / ton, 150?
200 yuan / ton.

Under the background of macroeconomic stabilization and improvement, the margin of demand has improved, which is expected to bring about sustained repair of profits.

With the increase in paper prices and the decline in pulp costs, the company’s pulp and paper-based papermaking profitability has promoted a quarter-to-quarter rise.

New production capacity has been gradually promoted. New production capacity that has been put into production will contribute to the performance in 2019, and the raw material structure will be further optimized.

At the end of Q1 2019, the company’s construction in progress increased earlier3.

5.9 billion to 9.

9.6 billion, the base projects are actively promoted.

1) Box board corrugated paper increases production capacity and contributes to increase. The supporting pulp line is gradually put into operation to optimize the raw material structure and expand the high-end box board paper market.

In 2018, a new 80-inch boxboard corrugated 北京夜生活网 paper project was put into operation mid-year. The new production line will contribute output in 2019, and the capacity of boxboard corrugated paper will be increased to 160 feet.

The 10-inch wood chip pulp production line and the 40-inch semi-chemical pulp production line have been completed and put into production in April and August 2018. The 20-inch natural color pulp production line and the Laos 40 waste waste pulp production line are expected to be used in July 2019.The company’s container board corrugated paper raw material structure will be further optimized to hedge against the risk of fluctuations in national waste price fluctuations; increasing the amount of cardboard box corrugated paper for external waste pulp will increase the quality of paper and expand the high-end container board market.

2) Laos dissolving pulp enters a stable production period in 2019, and the cost advantage contributes to the performance increase.

The company’s Laos 30 oxidant chemical pulp / dissolving pulp project converted to dissolving pulp in Q4 of 2018 and entered a stable production period in 2019. The project has its own forest land + 7-year tax-free period + freight savings + low labor costs and other large cost advantages, solubilizing pulp is profitableCapabilities will be further enhanced.

The company’s management capability and incentive level are benchmarks in the industry, and the papermaking leader with growth attributes maintains its overweight.

The company is a leader in cyclic papermaking with the attributes of growth stocks, as well as a benchmark for management and incentives for papermaking enterprises.

As the margin of liquidity improves and the renminbi continues to appreciate, the company’s PB is estimated to be at the bottom of history. As the overall market sentiment picks up, it is estimated to gradually repair.
We maintain our profit forecast for 2019-2021 attributable net profit to 21.

03 billion, 24.
24 ppm and 26.

480,000 yuan, corresponding to 0 EPS in 2019-2021.

81 yuan, 0.

94 yuan and 1.

02 yuan, currently total (7.

00 yuan / share) corresponding to PE for 2019-2021 is 8.

6 times, 7.

4 times and 6.

8 times, the current PB is 1.

4 times, maintaining overweight.

Doze in the afternoon, take a nap in science

Doze in the afternoon, take a nap in science

The fierce social competition and the accelerated pace of life will inevitably lead many people to work and have no time to take care of lunch break.

In fact, after a morning’s work and study, the human body consumes too much energy. Taking a nap after lunch can effectively compensate the human brain. Physical energy consumption is a great substitute for health.

  From a physiological point of view, the excitement of human brain cells can generally last 4?
After 5 hours, it will go into a suppressed state.

Especially after lunch, the blood supply of the digestive tract is significantly increased, and the blood supply of the brain is significantly reduced, resulting in a corresponding decrease in the oxygen and nutrients entering the brain with the blood flow. Therefore, the body’s circadian clock appears a sleep rhythm, which makes people feel debilitated, Sleepy feeling.

At this time, the body needs to make short-term adjustments to eliminate fatigue, restore physical strength, and stabilize the balance of nervous system functions.

  ”Siesta” is the most recommended “healthy living habits” by experts, which can not only significantly improve immunity, but also quickly relieve boredom, and improve mood and energy.

  Stores in Spain close at 2:30 pm and open again at 5 pm.

It turned out that the Spaniards took part in the “Siesta Movement for All” for two and a half hours every day for everyone to have a good nap.

  In the United States, “learning siesta” has become the latest fashion, and many companies have expressly stipulated that employees are encouraged to take a nap during the noon, gradually invigorate their spirits, and cope with more work in the afternoon.

  Afternoon Snoring 3 Great Benefits1.

Higher immunity Immunology experts say that in order to help digestion after lunch, the body will automatically switch to parasympathetic nerve conduction. At this time, taking a short sleep can more effectively stimulate the lymphocytes in the body and enhance the immune cell activity.

  2.

Cardiac Overstrength Spanish medical research shows that siesta for 30 minutes a day, the hormone secretion in the body is more balanced, and the incidence of cardiovascular diseases can also be reduced by 30%.

  3.

A better mood for psychologists at Harvard University in the United States wrote a report published in the latest issue of Natural Neuroscience, showing that snoring in the afternoon can improve mood, reduce tension and relieve stress-the effect is like falling asleepSeconds all night (8 hours) So how do you take a nap scientifically?

  First of all, siesta should not be too long, preferably within 1 hour.

  Physiological studies show that human sleep is divided into two stages of light sleep and deep sleep.

Normally, people fall asleep at 80?
After 100 minutes, it gradually changed from light sleep to deep sleep.

During deep sleep, the inhibitory processes of the brain’s central centers are significantly strengthened, many capillary networks in the brain tissue are temporarily closed, cerebral blood flow is reduced, and the body’s metabolism level is significantly reduced.

If people suddenly wake up in the deep sleep stage, the deeper inhibition process in the cerebral cortex cannot be lifted immediately, and the closed capillary network cannot be opened immediately, which will inevitably cause a transient insufficient blood supply to the brain and a temporary function of the autonomic nervous systemThe body is very nervous and uncomfortable.

This discomfort will last for about 30 minutes before disappearing.

It can be seen that the siesta time is not as long as possible, but it should be within 1 hour. This can effectively eliminate fatigue and prevent you from falling asleep too hard to wake up.

  First of all, it is not advisable to take a nap immediately after a meal.

  Do not sit or lie down immediately after meals. Stand properly for 30 minutes, during which you can wash dishes, place flowers, etc.

Then walk downstairs for 30 minutes to help digestion.

Then you can sleep, it is best to only sleep for 30 minutes, many friends said that after a nap, it hurts.

But I still want to sleep after sleeping, and my head hurts a lot because of the lack of oxygen in your head.

Because the stomach is full of undigested food after lunch, and then immediately lying down and overturning causes a feeling of fullness.

The correct way is to do some light activities after lunch, such as walking, rubbing your abdomen, etc., and then taking a nap, which will help the digestion and absorption of food.

  Third, pay attention to sleeping posture.

  It is often seen that someone is napping while sitting in a chair or sofa while nap, and some people are lying on the table and sleeping.

In fact, these practices are not scientific.

When the body is sleeping, muscles relax, heart rate slows, blood vessels dilate, blood pressure decreases, and blood flowing into the brain is relatively reduced.

Especially after lunch, the breakthrough blood enters the body. At this time, if you sit and sleep again, the brain will be deprived of oxygen for a long time, which will cause people to feel discomfort such as head weight, fatigue, and soft legs.

Lying on the table and sleeping will compress the upper and lower, obstruct breathing, and increase the burden on the heart and lungs.

It is generally believed that the sleeping position is the right position, because it can reduce the burden on the heart and increase blood flow to the liver, which is beneficial to the digestion and metabolism of food.
But in fact, due to the correction of the nap time, it is not necessary to force the sleeping to the left, to the right, to lie flat, as long as you can fall asleep quickly.

Elderly eat more grains is good for health

Elderly eat more grains is good for health

The grains we usually say are actually a “big family”: millet, corn, coarse rice, buckwheat, barley, oats, sweet potatoes, black beans, broad beans, red beans, mung beans, kidney beans, peas, etc. According to experts,Nutritional value is higher than refined flour and rice.

Contains many nutritional ingredients of health, Yishou and anti-cancer and anti-cancer substances. The characteristics and nutritional value of several kinds of cereals are introduced below. Millet is a granular finished grain after millet has been milled off the seed coat. The grains are small and oval.The color is milky white or pale yellow.

Divided into previous millet, waxy millet and mixed millet.

Its nutritional content is based on dry matter: it contains about 10% protein, 20-39% crude, and 0 crude fiber.

6-18% and calcium, phosphorus, iron and other trace elements and vitamin B group millet are easily digested and absorbed by the human body, regular consumption of millet can develop kidney qi, in addition to stomach heat, urination, especially suitable for maternal, young children and patients.

  Mung bean is a short-day, high-temperature crop. It can be grown in most other areas. Bright mung beans and green mung beans are divided according to performance and use. Bright mung beans have a green skin, shiny, sandy, and difficult to boil, but they have high germination rate.Raw sprouts.

The surface of the green mung bean is matte, sandy, and easy to rot. It is suitable for various foods.

  Main nutritional ingredients: 25% -32% protein, crude aunt 0 on dry matter basis.

6% -2.

3%, contains various amino acids, vitamins and iron, calcium, phosphorus and other minerals required by the human body. Iron content occupies the first place in food, mung beans are high in protein and low in feces.

Chinese medicine believes that the taste is sweet and cold, and it has the functions of cooling and detoxifying, stopping diarrhea and diuresis, swelling and lowering qi, removing heat and nourishing and strengthening.

  Corn is one of the main edible grains. It is divided into four categories according to grain color and grain quality: yellow corn, white corn, waxy corn, and mixed corn.

Main nutritional ingredients: protein by substance

7% -12.

9% crude aunt, 2.

6% -4.

6%, crude fiber 1.

9% -2.

9%, contains calcium, phosphorus, iron, carotene and vitamins.

Its sexual Ganping, has hemostatic and antihypertensive and diuretic and choleretic effects.

  Cereals mainly contain vitamin E, which can damage brain cell metabolism and delay aging.

With the research of anti-cancer diet therapy, experts have found that grains generally contain anti-cancer substances, so eating more grains can strengthen your body and make you healthy.

On clothing color and female psychology

On clothing color and female psychology

Surveys have found that the color a person prefers often represents the color of his personality and emotions.

So, psychologist Peter?

Dr. Luo Fu believes that a person’s choice of clothing color and clothing can often be considered psychological, which is more obvious to women.

  People who focus on the color of clothing and like complex clothing are often more practical and confident, but love to dominate people, feelings are impulsive, and easy to fall into vanity. People who like light clothing and simple clothing are often more introverted and liveSimple, gentle and quiet, but easy to lack self-confidence, rely on mental illness, not good at acting independently.

Because women are affected by their mood when choosing which clothes to wear, women often trim her mood of the day from the clothes that women change every day.

  The color of female clothing also expresses her personality.

  Women who like to wear red clothing are considered “young people with rich aspirations”. They often feel dissatisfied, adventurous and follow fashion, but their fickle temperament is often elusive.

  Women who like green are considered to be “tough and practical mothers.” In life, they stay calm, act prudently and work hard, but are afraid of taking risks and being forward-looking. They are introverted and often suppress their desires. They are ashamed to take the initiative in their relationships.

  In addition, people who like white often make people feel far away but not close; those who like purple may be more romantic; those who like yellow are naive; those who like blue are sincere and sincere and full of fantasy; they like blackPeople restrain their feelings from being exposed but eager to care and love . Of course, this classification seems a bit too simple. There are often many colors that one likes, which cannot be generalized.

However, knowing what color a woman prefers may help to understand her heart.

Ligustrum

Ligustrum

Brief introduction of efficacy classification: tonic medicine efficacy: tonic liver and kidney; clear deficiency fever; genus of eye genus: Oleaceae Latin name: Fructus Ligustri Lucidi Pharmacology (toxicology): Ligustrum lucidum is very toxic to animals, rabbits take once75g of fresh ripe fruit without poisoning.

  Indications: Dizziness; soft waist and knees; nocturnal emission; tinnitus; premature whiteness and hot flashes of bone steam; dark and unclear ecological environment: born in sparse forests or dense forests below 2900m above sea level, mostly cultivated in courtyards or roadsides.

  Harvesting and Storage: 4 after Ligustrum Transplantation?
The results begin in 5 years. When the fruit turns black and has white powder every December, it is layed down to remove stalks, leaves and impurities. It is dried or dried in hot water.

  Resource distribution: distributed in Shaanxi, Gansu, Zhejiang, Jiangsu, Yunnan, Guizhou, Guangdong and other places.

  Medication contraindications: spleen and stomach deficiency cold diarrhea and yang deficiency should not be taken.

“Ben Cao Jing Shu”: when mixed with spleen and stomach medicine and pepper red warming, the same application, or you may have abdominal pain as a leak.

  Medicinal properties: This product is a virgin virgin plant of the family Oleaceae.

Dry ripe fruits.

Winter fruits are harvested when they are mature, the branches and leaves are removed, and they are slightly steamed or boiled in boiling water and dried; or dried directly.

  Oval, oval or kidney-shaped, 6?
8.

5mm, diameter 3.

5?
5.

5 mm.

The surface is black-purple or gray-black, with uneven crests, stalk marks at the base or with a clipboard and short stems.

Light body.

The outer skin is thin, the middle skin is soft, easy to peel off, the inner skin is woody, yellow-brown, with longitudinal ribs, and the seeds are usually 1 grain, kidney-shaped, purple-black, oily after opening.

Odorless, sweet and slightly bitter.

Medicinal properties: sweetness, bitterness, coldness, and classics: liver, kidney, efficacy: nourishing liver, kidney and yin, black eyesight.

  Indications: For liver and kidney yin deficiency, backache, tinnitus, early whitening; dim eyes, dim vision; yin deficiency and fever.

  Dosage: Jianbi, 10?
15g.

  Pharmacological effects

Lipid-lowering and anti-arteriosclerotic powder of Ligustrum lucidum 20g / only mixed into the food and fed, it can reduce the serum cholesterol and triglyceride content in experimental hyperlipidemia rabbits, thereby causing aortic lipid plaque and coronaryReduced atherosclerotic plaque formation.

Ligustrum lucidum oleanolic acid 30mg / kg was mixed into a drink and fed to rats, 0.

4% oleanolate suspension 0.

5ml was administered to rabbits by gavage. For hyperlipidemia rats, both rabbits had hypolipidemic effect.

Oleanolic acid at 30 and 60 mg / kg was fed to Japanese quail for 8 weeks, which significantly reduced serum total cholesterol, lipid peroxide, total cholesterol content in the arterial wall, and reduced the incidence of atherosclerosis.

  2.

Hypoglycemic oleanolic acid is injected subcutaneously at 50, 100 mg / kg for 7 consecutive days, which can lower blood sugar in normal mice. It has preventive and therapeutic effects on diabetes in mice caused by tetratoluenesulfonic acid, and it can also fight against epinephrine or glucose.Mice have elevated blood sugar.

  3.

Anti-liver damage oleanolic acid 30, 50, 100 mg / kg subcutaneous injection can inhibit the increase of serum alanine aminotransferase (SGPT) in rats induced by carbon tetrachloride. For rats called carbon tetrachloride, QiSubcutaneous injection of oleic acid at 50 and 100 mg / kg can also decrease SGPT.

70mg / kg oleanolic acid can reduce liver damage caused by carbon tetrachloride. Histological observation, hepatocyte vacuole degeneration, looseness, hepatocyte necrosis, and lobular interstitial toxicity are all milder than corresponding ones.
Oleanolic acid 2mg / subcutaneous injection, for 6-9 weeks, has an effect on liver cirrhosis in rats caused by high-fat food and carbon tetrachloride.

Electron microscopy observation: In carbon tetrachloride-induced liver injury rats, oleanolic acid 20 mg / subcutaneous injection, mitochondrial swelling and endothelial reticulum vesicle transformation of transformed hepatocytes were alleviated.

  4.

Effects on the body’s immune function 4.

1 Effect on non-absolute immunity

1.

A Ligustrum lucidum that increases the number of axial leukocytes can significantly increase the number of internal leukocytes. Its active ingredient is oleanolic acid.
Alcoholic extracts can restore leukopenia in mice caused by cyclophosphamide (cy).
Steamed Ligustrum lucidum 480mg / kg has no effect on the white blood cells of normal mice, but it can correct the decrease of white blood cells caused by prednisone (25mg / kg, ip).
4.1.2 Effect on phagocytic function of reticuloendothelial system Macrophage viability was observed by clearance rate of foreign bodies in blood.
It is found that ig steamed Ligustrum lucidum 240mg / kgx5d can significantly increase the clearance index of iv carbon particles in mice and enhance the activity of the reticuloendothelial system; Ligustrum lucidum 480mg / kg has no obvious effect.
Ligustrum decoction 12.

5g / kgx7d had no significant effect on the clearance index, while 25g / kgx7d significantly inhibited the phagocytic activity of the reticuloendothelial system.
  4.2.Effects on specific immunity 4.
2.1 on cellular immune function Ligustrum lucidum can significantly improve T lymphocyte function.
Ligustrum lucidum water extract 0.
02ml significantly enhanced the lymphocyte proliferation caused by its appropriate amount of PHA, COA and PWM in vitro, and also significantly enhanced the rat local graft-versus-host response (GUH) caused by xenogeneic (human) lymphocytes, possibly due to partial elimination or eliminationThe effect of weak suppressor T cells is achieved.
Ligustrum lucidum polysaccharide (LLPS) can enhance the proliferation response of mouse spleen lymphocytes to ConA stimulation: 3H-TdR incorporation value (Cpm) 10mg / kg administration group (39308).

1 ± 6208) increased by about 120% compared with the control group (17959 ± 4508), P <0. 01, 50mg / kg administration group (2979 ± 3625) increased by about 70% compared with the control group, p <0. 07. Ligustrum lucidum decoction can promote the delayed-type hypersensitivity induced by SRBC. It shows that Ligustrum lucidum can enhance cellular immune function. Oleanolic acid 40mg, taken 3 times a day for 1 to 2 months, can improve the immune function of tumor patients. The phagocytosis of macrophages and rosettes of blood lymphocytes were significantly improved by the vesicle method.   Ligustrum lucidum induces M in both water and alcohol extracts? The effect of IL-1, and the water extract is stronger than the alcohol extract. This result reveals that the immune promotion effect of Ligustrum lucidum may be related to the induction of M? -IL-1 related. At the same time, Ligustrum lucidum promotes the activity of T cells by enhancing the activity of cell surface receptors. Ligustrum lucidum may be a better immunoregulatory drug for the low immune function caused by too high Ts activity.   4.2.2 on humoral immune function Ligustrum lucidum has the effect of enhancing humoral immune function. Ligustrum decoction ig12 for 7 consecutive days. 5 ~ 25g / kg can increase the weight of thymus and spleen of mouse immune organs; large dose can increase the weight of spleen of adult rats. Steamed Ligustrum lucidum 240mg / kg, 480mg / kg × 7 days can significantly increase the spleen, thymus, abdominal lymph nodes and adrenal glands of C57BL mice. Ligustrum lucidum polysaccharides were injected once a day for a total of 100 mg / kg for 7 days, which increased the spleen weight of LACA mice by about 40% compared with the control group, and 50 mg / kg increased the spleen weight of mice by about 30% compared with the control group. Ligustrum lucidum decoction can significantly increase the activity of serum hemolysin antibodies in mice, and can also increase the serum IgG content of normal mice, and counteract the immunosuppressive effect of Cy;It can also increase the serum IgG in mice, and can increase the IgG content of prednisone immunosuppressed mice. It can still clearly indicate that mice remember the activity of hemoglobin antibody; Ligustrum lucidum polysaccharides against Cy50mg / kgip caused byThe tumor cell-bearing mice (S180) had a low inhibitory effect on the lymphocyte proliferation response, and Ligustrum lucidum polysaccharides obviously counteracted the immunosuppressive effect of Cy.   4.Inhibition of allergic reactions by Ligustrum lucidum 12.5,25g / kgig mice for 7d; the same dose of 5dig rats, different doses of Ligustrum lucidum on mice or rats passive skin allergic reaction (PCA) significantly inhibited. Ligustrum lucidum decoction can reduce the percentage of degranulation of rat mast cells and prevent the increase of rat capillary permeability caused by histamine; administration before antigen challenge can inhibit DNCB-induced contact dermatitis in mice; Ligustrum lucidumThe administration of 25g / kg of seed after antigen challenge can also significantly inhibit the contact skin process of mice caused by DNCB; reduce the active and reverse passive Arthus response in rats; 20g / kg of Ligustrum lucidum significantly reduces the total serum complement of guinea pigs. This shows that Ligustrum lucidum has obvious inhibitory effects on type Ⅰ, Ⅱ, and Ⅳ allergies.   5.The anti-inflammatory effect was confirmed by Ligustrum lucidum using various experimental antibacterial models. 5g / kg, 25g / kg daily ig, for 5 consecutive days, p-xylene caused swelling of the auricles of mice, increased capillary permeability of the abdominal cavity of mice caused by acetic acid, and carrageenan, egg white, and formaldehyde-induced rat feetThe swelling and expansion of the pad significantly inhibited; Ligustrum lucidum 20g / kg × 3 days ig can significantly reduce the release of PGE in rat tissues; Ligustrum lucidum 20g / kg × 7 days can inhibit the proliferation of rat cotton ball granulation tissue,This is accompanied by an increase in adrenal weight. Its anti-inflammatory mechanism may involve the following aspects: ① activating the pituitary-adrenocortical system and promoting the release of corticosteroids; ② inhibiting the synthesis or release of PGE. In addition, Ligustrum lucidum can reduce serum complement activity in guinea pigs and increase the permeability of rat skin capillaries caused by the antibiotic medium histamine. Therefore, the anti-inflammatory mechanism of Ligustrum lucidum may also include the aforementioned effects.   6. Anti-cancer, anti-mutant oleanolic acid has antitumor effect on mouse sarcoma-180. Ligustrum decoction 12. 5, 25 g / kg gavage, oleanolic acid 50, 100 mg / kg subcutaneous injection, can significantly inhibit the increase of micronucleus rate in mice caused by cyclophosphamide and urethane.   7. Studies on the effect on the endocrine system show that Ligustrum lucidum contains both estrogen-like substances and androgen-like substances. Ligustrum lucidum 428 is contained in Ligustrum lucidum by radioimmunoassay. 31 pg / g, estradiol 139. 02pg / gram. It is proved that Ligustrum lucidum has both insulin pill-like and estradiol-like hormone analogs, that is, the same drug has a two-way regulating effect. Traditional Chinese medicines such as Ligustrum lucidum and kidney-yin produced estrogen-like effects on the vaginal mucosa of indifferent mice, and the number of large follicles in the ovaries of rabbits in the medication group increased significantly, and estrogen increased.   8.Impact on the hematopoietic system Ligustrum lucidum has a promoting effect on red blood cells. Ligustrum lucidum can promote the growth of CFU-E using the diffusion box plasma clot method. CFU-E / 5 × l4 is 128. 6 ± 11. 4 (8), CFU-E / femur was 62040 ± 5450 (8), CFU-E in femur was significantly higher than that in NS group, but CFU-D was significantly reduced. Morphological analysis of bone marrow cells in mice after treatment showed that the percentage of red blood cells in the Ligustrum lucidum group was 47. 3 ± 2. 99 (6) is better than NS37. 3 ± 2. The 86 (6) group increased, and the percentage of granulocytes was 37. 6 ± 3. 96 (6) was 46 compared with NS group. 6 ± 6. 26 (6) decreases, and the ratio of grain red changes accordingly.   9. Protective effect on chromosomal damage caused by cyclophosphamide Protective effect on chromosomal damage caused by cyclophosphamide and urethane Micronucleus test method proves that Ligustrum lucidum decoction pol2. 5 g / kg 25. 0 g / (kg d) × 6, oleanolic acid ih50mg / kg, 100mg / (kg · d) × 7 pairs of cyclophosphamide ip50mg / (kg · d) × 2, urethane 500mg / (kg · d) × 4, caused by ipChromosome damage in mice has a protective effect and can reduce its micronucleus rate. 10. Anti-HpD photochlorination Ligustrum lucidum can counteract the photooxidation of HpD, and its application in vivo can significantly alleviate the photosensitivity of HpD to the skin of mice. Ligustrum lucidum 60mg crude drug / ml can significantly reduce the increase of malondialdehyde content in red blood cells caused by HpD5ug / ml combined with light exposure for 10min, and inhibit 57. 7%, obviously against the inhibition of erythrocyte membrane acetylcholinesterase activity, resistance against 49. O%, 120mg / ml, against supplement 53. 3%, mouse ipHpD20mg / kg, light exposure for 4h, Ligustrum lucidum 20g crude drug / kg, ip 1 time, significantly alleviate ear photosensitivity. Ligustrum lucidum produces 1O2 less efficiently than digits. 5 × 10-4 times.   11. Other effects Ligustrum lucidum still has cardiovascular effects such as strengthening heart, dilating coronary vessels, dilating blood vessels; diuretic, antitussive, laxative, antibacterial and so on. Oleanolic acid has some cardiotonic and diuretic effects; mannitol has a slowing effect; it also contains a large amount of glucose; these may be associated with strong effects.